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Allison Sit

SOCU Faculty Research: Thiamidol for Hyperpigmentation

By Skin of Color Update Agenda

hyperpigmentation

Skin of Color Update faculty are experts in skin of color dermatology. Eight faculty members were involved with this recent Journal of Drugs in Dermatology article on Thiamidol as a treatment for hyperpigmentation.

Drs. Cheri Frey, Pearl Grimes, Valerie Callender, Andrew Alexis, Hilary Baldwin, Nada Elbuluk, Susan Taylor, and Seemal Desai conducted the review of pre-clinical and clinical safety and efficacy data of Thiamidol formulations. Thiamidol or isobutylamido thiazolyl resorcinol, has been identified as the most effective human tyrosinase inhibitor out of 50,000 compounds screened. The researchers wrote that Thiamidol appears to be safe and effective and should be considered when recommending over-the-counter treatment options to patients with hyperpigmentation.

For the latest research and updates in the treatment of hyperpigmentation, attend Skin of Color Update. Register today!

SOCU Faculty Research: Low-dose Spironolactone for Hair Loss in Women

By Sessions

low-dose spironolactone

Skin of Color Update faculty member Maryanne Makredes Senna, MD, FAAD, published research in the Journal of Drugs in Dermatology on the efficacy of low-dose spironolactone for hair loss in women.

Dr. Makredes Senna and her colleagues conducted a retrospective chart review of adult women with female pattern hair loss who were treated with 50 mg or less daily of spironolactone either alone or in combination with other therapies. Results showed a statistically significant decline in the average Sinclair Score in patients treated with spironolactone as monotherapy (2.63 to 1.95) after one year. Including patients on other therapies, such as such as topical minoxidil 5% foam or low-level light laser treatment, results also showed a significant decrease (2.47 to 1.81) after one year.

Attend Dr. Makredes Senna’s hair loss sessions at Skin of Color Update for the latest in treatments for scarring and non-scarring alopecias. Register today!

SOCU Faculty in the News: Dr. Karan Lal

By Skin of Color Update Agenda

pediatric psoriasis

Skin of Color Update faculty member Karan Lal, DO, FAAD, wrote the August cover story for Dermatology Times on the hidden burdens of pediatric psoriasis.

In the article, Dr. Lal addresses the need for early intervention and awareness of systemic comorbidities linked to pediatric psoriasis, including uveitis, arthritis, obesity, type 2 diabetes (T2D), and metabolic syndrome. Dr. Lal also comments on  available therapies and treatment obstacles in this patient population.

Dr. Lal will participate in an expert discussion at Skin of Color Update on addressing comorbidities in dermatologic disorders, including psoriasis and hidradenitis suppurativa. This discussion will also address the potential role of GLP-1 agonists. In addition, Dr. Lal will present on pediatric dermatology pearls for treating patients with skin of color.

Register for Skin of Color Update and attend lectures by premier experts in dermatology on topics that impact your patients.

JDD Video Abstract with Dr. Cheri Frey

By Aesthetic Dermatology

pre-aging

Skin of Color Update faculty member Cheri Frey, MD, FAAD, recently shared a video abstract of her Journal of Drugs in Dermatology study evaluating the benefits of acetyl dipeptide-31 amide (AP31) for pre-aging skin.

Watch as Dr. Frey outlines the signs of pre-aging and the goal of prejuvenation. Learn how Dr. Frey and her colleagues conducted their research on AP31 and their results. Find out her takeaways and how dermatologists are now addressing aging skin before changes are visible.

Dr. Frey will lecture on cosmeceuticals and exosomes at Skin of Color Update. Register today!

American Journal of Managed Care: SOCU News Coverage

By Media Coverage

hidradenitis suppurativa

American Journal of Managed Care wrote about a poster from Skin of Color Update 2024 that identified the populations most affected by hidradenitis suppurativa (HS). Researchers found those who are Black, female, a tobacco smoker, a public insurance holder, or disabled are more likely to have an HS diagnosis. The authors maintain that understanding the sociodemographics of HS allows dermatologists to better reach at-risk populations.

Register now for Skin of Color Update 2025 and increase your knowledge of hidradenitis suppurativa and other dermatologic conditions that disproportionately affect patients with skin of color.

Spotlight on STDs in Skin of Color

By Sessions

STDs in skin of color

At the 2024 Skin of Color Update, Theodore Rosen, MD, FAAD, highlighted the critical role dermatologists play in recognizing and treating sexually transmitted diseases (STDs), many of which present with skin findings. His talk focused on the disproportionate burden of STDs in patients with skin of color, the unique clinical presentations of STDs, and the importance of early detection and equitable access to care.

  • Epidemiology & Disparities: In the U.S., 2.5 million STDs are diagnosed annually. African American, Hispanic, American Indian, and Alaska Native populations experience disproportionately high rates of STDs likely due to barriers in healthcare access and lack of knowledge of STD care.
  • Syphilis: Cases of primary, secondary, and congenital syphilis continue to rise, with a record number of congenital cases in 2022. Secondary syphilis in patients with skin of color may mimic psoriasis or appear as nodular or annular lesions. Early recognition is essential to reduce congenital syphilis.
  • Monkeypox (Mpox): Rates have declined since 2022, but Black and Hispanic men who have sex with men remain disproportionately affected. Full vaccination is underutilized due to lack of availability, and resistance to tecovirimat is emerging.
  • HSV (Herpes Simplex Virus): Overall rates are declining, but non-Hispanic Black individuals remain disproportionately affected. Hypertrophic/vegetative HSV-2, more common in immunocompromised patients with skin of color, requires biopsy, appropriate immunostaining, or viral culture (PCR) to make a diagnosis. Treatment requires multimodal therapy.
  • Other STDs: Chancroid, donovanosis, and lymphogranuloma venereum are now rare in the U.S., and mostly limited to specific populations.
  • Testing & Resources: Patients can access free or at-home STD testing through CDC resources.

Key Takeaway: Rising STD rates, especially syphilis, highlight the urgent need for targeted screening, culturally competent care, and better education and prevention strategies for patients with skin of color.

This session summary was written by Dr. Olive Osuoji and published on Next Steps in Derm.

Register for Skin of Color Update for more medical dermatology updates.

Scarring Alopecias in Patients With Skin of Color – From SOCU 2024

By Sessions

scarring alopecias

At Skin of Color Update 2024, Susan Taylor, MD, FAAD, delivered an expert overview on diagnosing and treating scarring alopecias in patients with skin of color. Her talk emphasized the unique clinical presentations, dermoscopic features, comorbidities, and culturally sensitive care needed to optimize outcomes in this underserved population.

Key Conditions Covered:

  1. Central Centrifugal Cicatricial Alopecia (CCCA)
    Most common in women of African descent, CCCA typically affects the vertex scalp but may also appear in atypical patterns. Men are often underdiagnosed due to its similarity to androgenetic alopecia.
  • Dermoscopic clues include peripilar white halos, pinpoint white dots, honeycomb pigmentation, and a “starry sky” pattern.
  • CCCA is associated with systemic comorbidities such as diabetes, hypertension, obesity, and even breast cancer.
  1. Lichen Planopilaris (LPP)
    LPP causes scarring hair loss with perifollicular erythema and scaling, and can vary in pattern and speed of progression.
  • Dermoscopic features include perifollicular hyperkeratosis and depigmented scarred plaques.
  • Dr. Taylor noted that scalp burning (rather than itching) is a distinguishing symptom, and emphasized examining the skin, nails, and mucosa for related lichen planus involvement.
  1. Frontal Fibrosing Alopecia (FFA)
    A variant of LPP, FFA commonly affects postmenopausal women but is increasingly recognized in men.
  • Presents as band-like anterior hairline recession, often with eyebrow loss or facial pigmentation changes.
  • Dermoscopic signs include the “lonely hair” sign and perifollicular erythema.
  • Dr. Taylor highlighted potential links to actinic damage and sunscreen or hair product allergens, recommending patch testing in select cases.
  1. Traction Alopecia (TA)
    TA results from chronic tension on the hair, often due to tight hairstyles like braids or extensions.
  • Early recognition is critical to prevent permanent loss.
  • Dermoscopic features include the “fringe sign,” broken hairs, hair casts, and the “flambeau sign.”
  • Dr. Taylor urged clinicians to take thorough hairstyling histories and counsel patients on protective styling to prevent or reverse damage.

Conclusion:

Dr. Taylor’s presentation provided a comprehensive, culturally attuned framework for diagnosing and treating scarring alopecias in patients with skin of color. She emphasized the use of dermoscopy, early intervention, and awareness of comorbidities and lifestyle factors to improve care. Her insights reinforced the need for personalized and informed dermatologic approaches to better serve this frequently overlooked patient group.

This session summary was written by Dr. Nidhi Shah and published on Next Steps in Derm.

Register for Skin of Color Update for more insights from Dr. Susan Taylor.

Inflammatory Skin Conditions in Children With Skin of Color – SOCU 2024

By Medical Dermatology

inflammatory skin conditions in children with skin of color

A keen eye is required when dermatology clinicians treat inflammatory skin conditions in patients with skin of color. Pediatric dermatologist Brandi Kenner-Bell, MD, FAAD, spoke with Next Steps in Derm at Skin of Color Update 2024 about what to look for when diagnosing inflammatory skin conditions in patients with darker skin tones, and what’s important to know when treating children.

Watch as Dr. Kenner-Bell shares the importance of knowing what treatments have FDA approval for use in children and which do not. Plus find out how pigmentary concerns should impact your course of treatment.

Register for Skin of Color Update for more pearls in treating inflammatory skin conditions in patients with skin of color.

Understanding Psoriasis at SOCU with Dr. Amy McMichael

By Medical Dermatology, Sessions

diagnosing and treating psoriasis in skin of color

August is Psoriasis Awareness Month. At Skin of Color Update 2024, Amy McMichael, MD, FAAD, delivered a comprehensive presentation on the unique challenges of diagnosing and treating psoriasis in patients with skin of color. She emphasized the importance of early recognition, tailored treatment plans, and addressing racial disparities in clinical research.

Unique Presentation in Skin of Color
Psoriasis often appears differently in darker skin tones, with violaceous or hypertrophic plaques, hyperpigmented thin plaques, or guttate (raindrop-like) lesions rather than the classic red, scaly plaques seen in lighter skin. Dr. McMichael recommended biopsy confirmation, especially since the appearance may evolve during treatment.

Treatment Strategies

  • Topicals: Ultrapotent topical steroids are often first-line, but non-steroidal alternatives (e.g., calcipotriene, roflumilast, tapinarof) may be used to reduce steroid-related side effects.
  • Systemics: For more severe cases, systemic treatments like methotrexate, cyclosporine, and acitretin can be effective, particularly in hypertrophic lesions.
  • Biologics: Although effective across all skin types, biologics are underutilized in patients of color due to limited representation in clinical trials.
  • JAK inhibitors and UV phototherapy were also discussed as viable options, especially for refractory disease or patients seeking non-biologic treatments.

Special Considerations
Treating areas like the scalp or groin requires attention to hairstyling practices and vehicle compatibility. Post-inflammatory hyperpigmentation (PIH) is a frequent concern in patients of color, often lingering after psoriasis clears. Dr. McMichael stressed setting realistic expectations and suggested adjunctive use of retinoids or skin-lightening agents alongside psoriasis treatments.

Addressing Disparities
Despite the broad availability of effective therapies, patients of color remain underrepresented in psoriasis research. Dr. McMichael pointed to the VISIBLE trial, which enrolled a racially diverse patient group, as a model for more inclusive studies.

Conclusion
Dr. McMichael underscored the importance of aggressive early treatment, cultural and clinical sensitivity, and diversifying clinical research to improve outcomes for patients of color. Education on pigmentary changes and tailored treatment strategies are key to managing both the physical and psychological impacts of psoriasis in diverse populations.

This session summary was written by Dr. Nidhi Shah and published on Next Steps in Derm.

Cosmetic Procedures in Patients with Skin of Color: Highlights from SOCU 2024

By Sessions

cosmetic procedures in patients with skin of color

At Skin of Color Update 2024, Dr. Cheryl Burgess delivered an insightful presentation on providing safe and effective cosmetic treatments for patients with skin of color. Her talk emphasized the importance of understanding both biological and cultural differences to minimize complications and enhance outcomes.

Dr. Burgess highlighted that, while all individuals have the same number of melanocytes, patients with darker skin have larger melanosomes, increasing their risk for hyperpigmentation. She also explained how cultural beauty ideals—such as preferences for lighter skin in Southeast Asia or fuller body figures in West Africa—can shape patient expectations and treatment goals.

Histologically, skin of color differs in fibroblast structure, melanin dispersion, and vascular reactivity, making it more prone to scarring and post-inflammatory hyperpigmentation. Dr. Burgess stressed careful diagnosis using tools like a Wood’s lamp and colorimeters, and advocated for test spots and low-concentration peels to ensure safety.

She identified the Nd:YAG 1064nm laser as the safest option for hair removal and pigmentation treatment, while advising against IPL due to risks of burns. Other effective technologies include radiofrequency and ultrasound-based treatments, which require cautious use.

Finally, Dr. Burgess underscored the need for cultural sensitivity in cosmetic enhancements, such as lip augmentation preferences among Black patients and body image norms in West Africa. Her presentation called for a personalized, informed approach to cosmetic dermatology that combines clinical skill with cultural understanding.

This session summary was written by Dr. Nidhi Shah and published on Next Steps in Derm.