A combination treatment regimen that includes a cosmetic brightener, dual antioxidant system, facial cleanser, sunscreen, and moisturizer could provide a new solution for moderate to severe facial hyperpigmentation disorders in skin of color patients, according to a poster presented at the Skin of Color Update 2021, held virtually September 10-12.1
“Hyperpigmentation disorders disproportionately affect individuals with skin of color,” wrote the authors. “These conditions are challenging to treat in patients with skin of color, and these disorders are often recalcitrant or relapsing and require continuous treatment.”
That poses an ongoing problem, they wrote. “The gold standard therapies containing hydroquinone (HQ) cannot be used for extended periods because of adverse effects [AEs],” they added. “Cosmetic topical therapies are in demand, but current options lack efficacy.”
In their view, “comprehensive treatment regimens are needed to adequately address hyperpigmentation.” The aim of their research was to evaluate the safety and efficacy of a comprehensive regimen that would include agents “that reduce melanogenesis or neutralize extrinsic stressors” when used together; a comprehensive HQ-free retinol-free cosmetic topical brightener (Lytera 2.0 (LYT2), SkinMedica) and a dual serum that provided antioxidant protection and skin repair support (Lumivive System (LVS), SkinMedica).